Six representative coronal slices of the T2 weighted MR images of TD-rats on day 14The marked areas represent abnormalities characterized by a significant increase in signal intensity that occurred on day 14 as compared to day 0 (p<0.01). (a,b) thalamus and corpus callosum; (c,d) thalamus; (e) superior and inferior colliculi; (f) superior cerebellar peduncle.
The ratio between pGluR1 and total GluR1 in the NAC of treated rats using western blot analysisRats treated with cocaine (Fig 2A). Rats treated with heroin (Fig 2C). Unpaired Student’s t-test revealed a significant difference between insulin and aCSF treatments (** p<0.005) in the cocaine treated rats. Representative films are shown (Fig 2B-cocaine and Fig 2D-heroin).
