- Six representative coronal slices of the T2 weighted MR images of TD-rats on day 14The marked areas represent abnormalities characterized by a significant increase in signal intensity that occurred on day 14 as compared to day 0 (p<0.01). (a,b) thalamus and corpus callosum; (c,d) thalamus; (e) superior and inferior colliculi; (f) superior cerebellar peduncle.
- The ratio between pGluR1 and total GluR1 in the NAC of treated rats using western blot analysisRats treated with cocaine (Fig 2A). Rats treated with heroin (Fig 2C). Unpaired Student’s t-test revealed a significant difference between insulin and aCSF treatments (** p<0.005) in the cocaine treated rats. Representative films are shown (Fig 2B-cocaine and Fig 2D-heroin).